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Functional Characterization of the Split Set and MYND Domain containing Methyltransferases Smyd2 and Smyd3

11 View(s), published at 2007, written by Mark Alan Brown, published by ProQuest
Functional Characterization of the Split Set and MYND Domain containing Methyltransferases Smyd2 and Smyd3

Functional characterization of the split set and mynd domain-containing methyltransferases, smyd2 and smyd3 by Mark Alan Brown Most histone lysine methyltransferases catalyze methyl transfer by way of the SET domain, a module encoded within many proteins that regulate diverse processes, including some critical for development.... Published date on: 2007 with total page: 161 pages. Publisher of Functional Characterization of the Split Set and MYND Domain-containing Methyltransferases, Smyd2 and S

Most histone lysine methyltransferases catalyze methyl transfer by way of the SET domain, a module encoded within many proteins that regulate diverse processes, including some critical for development and proper progression of the cell cycle. One such group of proteins, the SET and MYND domain (Smyd) family have been demonstrated to be direct regulators of tumorigenesis and essential developmental processes. Presented here is a functional characterization of two members of that family, Smyd2 and Smyd3.

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